CAGRILINTIDE

Cagrilintide is a long-acting, lipidated synthetic analog of the pancreatic hormone amylin, engineered to achieve extended half-life through fatty acid conjugation that facilitates albumin binding and slows systemic clearance. It functions as a dual agonist at amylin receptor subtypes 1 and 3 (AMY1R and AMY3R), activating both homeostatic and hedonic regulatory circuits in the central nervous system. Research in clinical and preclinical models, including phase 2 trials in combination with semaglutide, has established it as a metabolic candidate under active investigation for body weight and related cardiometabolic parameters. Supplied as lyophilized powder, ≥99% purity. Store at -20°C. Research use only. Not for human consumption.