GHK-CU

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide found in human plasma, saliva, and urine that chelates copper(II) and serves as an endogenous signaling molecule whose plasma concentrations decline significantly with age. Research across fibroblast culture models and preclinical wound healing studies has characterized its capacity to stimulate synthesis of collagen, elastin, and glycosaminoglycans, modulate matrix metalloproteinase/TIMP ratios, and promote balanced tissue remodeling with reduced fibrotic outcomes. Broader transcriptomic analyses have identified GHK-Cu as a regulator of over 4,000 human genes, with particular enrichment in pathways governing DNA repair, antioxidant response, and anti-inflammatory signaling. Supplied as lyophilized powder, ≥99% purity. Store at -20°C. Research use only. Not for human consumption.